Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Role of Mitochondria in the Pathophysiology of Skeletal Muscle Insulin Resistance

27 Oct 2009

Abstract excerpt

Multiple organs contribute to the development of peripheral insulin resistance, with the major contributors being skeletal muscle, liver, and adipose tissue. Because insulin resistance usually precedes the development of type 2 diabetes mellitus (T2DM) by many years, understanding the pathophysiology of insulin resistance should enable development of therapeutic strategies to prevent disease progression. Some...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Metabolism, Diabetes, and Cancer
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19861693
DOI: 10.1210/er.2009-0003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Role of Mitochondria in the Pathophysiology of Skeletal Muscle Insulin ResistancePMID 19861693Read ↗

Mitochondrial dysfunction and insulin resistance: an updateSemantic proximity Read ↗

Mitochondrial Dysfunction as a Factor of Energy Metabolism Disorders in Type 2 Diabetes MellitusSemantic proximity Read ↗

Mitochondrial Dysregulation in the Pathogenesis of Diabetes: Potential for Mitochondrial Biogenesis-Mediated InterventionsSemantic proximity Read ↗

An exercise-modifiable mitochondrial basis for skeletal muscle insulin resistance in humansSemantic proximity Read ↗

Mitochondrial Dysfunction in Diabetes: Shedding Light on a Widespread OversightSemantic proximity Read ↗

[Molecular mechanisms underlying insulin resistance in skeletal muscle].Semantic proximity Read ↗

Mitochondrial dysfunction in type 2 diabetes mellitus: an organ-based analysisSemantic proximity Read ↗

Perspectives and Potential Applications of Mitochondria‐Targeted Antioxidants in Cardiometabolic Diseases and Type 2 DiabetesSemantic proximity Read ↗

Mitochondrial regulation of β-cell function: maintaining the momentum for insulin release.Semantic proximity Read ↗

A review of mitochondrial dysfunction in diabetic sarcopenia: Mechanisms, diagnosis, and treatment approachesSemantic proximity Read ↗

The pathogenetic role of β-cell mitochondria in type 2 diabetesSemantic proximity Read ↗

Insulin Resistance Mediates Crosstalk between Skeletal Muscle and the Heart to Prevent Cardiac DysfunctionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.