Article

IsoSpace: Chemistry-Informed Dimensionality Reduction and Automated Isotope Candidate Detection in Imaging Mass Spectrometry

2025-12-02

Abstract excerpt

Imaging mass spectrometry (IMS) experiments simultaneously map thousands of ion species throughout tissue. Its high-dimensionality makes human interpretation difficult and dimensionality reduction (DR) methods are common to facilitate exploration. Traditional DR methods, such as principal component analysis (PCA), are general approaches, designed to work across application domains. They are usually unaware of, and...

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Literature Corpus work: de0cb3a9-f89a-5118-97e5-1c7774550700
DOI: 10.64898/2025.11.30.691393

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