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IsoMobil: Resolving Molecular Ambiguity in Mass Spectrometry-based Spatial Omics Through Ion Mobility

2026-08-13

Abstract excerpt

Molecular imaging by imaging mass spectrometry (IMS) has become a key modality for spatial proteomics, lipidomics, glycomics, and metabolomics. It maps hundreds to thousands of molecular species con-currently throughout tissue without prior labeling. However, reporting thousands of ion images makes IMS measurements very high-dimensional, complicating interpretation. Furthermore, IMS data contain implicit chemical...

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Literature Corpus work
664fbe91-96c4-59db-95b6-177be24b2535
DOI
10.64898/2026.08.07.743457
Open publication

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