Article

Signal Strength Aware Latent Spaces Reveal Molecularly Distinct Substructures within Human Kidney Tissue

2026-01-16

Abstract excerpt

As datasets grow increasingly high-dimensional and complex, distinguishing a condensed set of interpretable underlying factors becomes essential. In spatial omics, for example, hundreds to thousands of molecular features per observation promise unprecedented biological insight. However, without meaningful latent representations, that potential remains markedly untapped. We propose a new approach based on the beta-...

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Literature Corpus work: 27bc03a8-a6f2-5271-9d96-a163a39aac23
DOI: 10.64898/2026.01.15.699686

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