Unlocking the Neuropeptidome using a Novel Endogenous Peptidomics Framework

Abstract excerpt

Endogenous peptides have garnered increasing attention over the past decade driven by the development of advanced analytical methods. However, large-scale investigations of peptides as potential disease biomarkers or drug candidates are still hindered by their challenging biochemical properties and the scarcity of specialized analytical tools. Among these, neuropeptides are particularly challenging to study due to...

Topics

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• Colorectal Neoplasms
• Histocompatibility Antigens Class I
• Mass Spectrometry
• Monoclonal and Polyclonal Antibodies Research
• Mutation
• Peptides
• Proto-Oncogene Proteins p21(ras)
• vaccines and immunoinformatics approaches

Identifiers and source

Literature Corpus work

5a402691-aec0-565e-a193-0ca1f33f3a40

DOI

10.1101/2025.06.12.659356