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Duplicated zebrafish ( <i>Danio rerio</i> ) inositol phosphatases <i>inpp5ka</i> and <i>inpp5kb</i> diverged in expression pattern and function

2022-09-02

Abstract excerpt

One hurdle in the development of zebrafish models of human disease is the presence of multiple zebrafish orthologs resulting from whole genome duplication in teleosts. Mutations in Inositol polyphosphate 5-phosphatase K ( INPP5K ) lead to a syndrome characterized by variable presentation of intellectual disability, brain abnormalities, cataracts, muscle disease, and short stature. INPP5K is a phosphatase acting a...

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Literature Corpus work
dde91a31-9e66-5698-9100-00eb77b32904
DOI
10.1101/2022.08.31.506059
Open publication

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Duplicated zebrafish ( <i>Danio rerio</i> ) inositol phosphatases <i>inpp5ka</i> and <i>inpp5kb</i> diverged in expression pattern and functionDOI 10.1101/2022.08.31.506059
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