Article

Ciliary protein CEP290 regulates focal adhesion via microtubule system in non-ciliated cells <sup>1</sup>

2023-04-03

Abstract excerpt

Almost all differentiated mammalian cells have primary cilia on their surface. Ciliary dysfunction causes ciliopathy in humans. Centrosomal protein 290 (CEP290) is a ciliary protein that causes ciliopathies, localizes at the cilial base in ciliated cells, whereas it localizes to the centrosome in non-ciliated proliferating cells. The cilia-dependent function of CEP290 has been extensively studied; however, the cil...

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Literature Corpus work: dd421a5b-b3f0-588d-9581-41fbdfa9d8b2
DOI: 10.1101/2023.04.02.535304

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