Article

Bovine lactoferrin inhibits inflammatory response and apoptosis in LPS-induced acute lung injury by targeting the PPAR-γ pathway

2023-12-12

Abstract excerpt

<h4>Background: </h4> Lactoferrin (LF) is an iron-binding multifunctional cationic glycoprotein. Previous studies have demonstrated that LF may be a potential drug for treating acute lung injury and acute respiratory distress syndrome. In this study, we explored the anti-inflammatory effect and mechanism of bovine lactoferrin (bLF) in acute lung injury using the RNA sequencing (RNA-seq) technology and transcriptom...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: dd41e5cf-eb0c-54a1-80c1-7ad68709a575
DOI: 10.21203/rs.3.rs-3709094/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bovine lactoferrin inhibits inflammatory response and apoptosis in LPS-induced acute lung injury by targeting the PPAR-γ pathwayDOI 10.21203/rs.3.rs-3709094/v1Read

Regulation of physiological and pathological Th1 and Th2 responses by lactoferrinThis paper is one of a selection of papers published in this Special Issue, entitled 7th International Conference on Lactoferrin: Structure, Function, and Applications, and has undergone the Journal's usual peer review process.Semantic proximity Read

The Multifaceted Functions of Lactoferrin in Antimicrobial Defense and InflammationSemantic proximity Read

New insights into the systemic effects of oral lactoferrin: transcriptome profilingSemantic proximity Read

ZBP1 aggravates acute lung injury in mice by promoting the macrophage inflammatory phenotype.Semantic proximity Read

rhMFGE8 Attenuates Endothelial-to-Mesenchymal Transition in Acute Lung Injury Induced by Lipopolysaccharide Through the BMP/Smad1/4/5/Snail Signalling PathwaySemantic proximity Read

Lactoferrin may inhibit the development of cancer via its immunostimulatory and immunomodulatory activitiesSemantic proximity Read

Exploring the mechanism of astaxanthin against lipopolysaccharide-induced acute lung injury by network pharmacology and experimental validationSemantic proximity Read

LACC1 attenuates LPS-induced acute lung injury by inhibiting inflammatory response in alveolar macrophage through LPAR3/PI3K/AKT/mTOR signaling pathwaySemantic proximity Read

<i>Lactobacillus rhamnosus</i> (LR) ameliorates acute respiratory distress syndrome (ARDS) via modulating the lung “Innate Lymphoid Cells (ILCs)-Mononuclear Phagocytic System (MPS)”Semantic proximity Read

Evaluation of Bovine Lactoferrin for Prevention of Late-Onset Sepsis in Low-Birth-Weight Infants: A Double-Blind Randomized Controlled TrialSemantic proximity Read

Lactoferrin and host defence: an overview of its immuno-modulating and anti-inflammatory propertiesSemantic proximity Read

Lactoferrin gene expression and regulation: an overviewSemantic proximity Read