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The Multifaceted Functions of Lactoferrin in Antimicrobial Defense and Inflammation

16 Aug 2025

Abstract excerpt

Lactoferrin (Lf) is a multifunctional iron-binding glycoprotein of the transferrin family that plays a central role in host defense, particularly in protection against infection and tissue injury. Abundantly present in colostrum, secretory fluids, and neutrophil granules, Lf exerts broad-spectrum antimicrobial activity against bacteria, viruses, fungi, and parasites. These effects are mediated by iron...

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PMID: 40867618
DOI: 10.3390/biom15081174

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