Article

Sensitive period-regulating genetic pathways and exposure to adversity shape risk for depression

2021-05-17

Abstract excerpt

Animal and human studies have documented the existence of developmental windows (or sensitive periods) when experience can have lasting effects in shaping brain structure or function, behavior, and disease risk. Sensitive periods for depression likely arise through a complex interplay of genes and experience, though this possibility has not been explored. We examined the effect of sensitive period-regulating genet...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: dd23be17-9545-50f1-9089-4f316be4376c
DOI: 10.1101/2021.05.13.21257179

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sensitive period-regulating genetic pathways and exposure to adversity shape risk for depressionDOI 10.1101/2021.05.13.21257179Read

Sensitive period-regulating genetic pathways and exposure to adversity shape risk for depressionSemantic proximity Read

Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics.Semantic proximity Read

Genetics, epigenetics, and neurobiology of childhood-onset depression: an umbrella review.Semantic proximity Read

Sex-specific hormone-sensitive regulatory architecture in adolescence as a scaffold for depression vulnerabilitySemantic proximity Read

New Insights into How Serotonin Selective Reuptake Inhibitors Shape the Developing BrainSemantic proximity Read

Prenatal stress and genetic risk: How prenatal stress interacts with genetics to alter risk for psychiatric illness.Semantic proximity Read

Epigenetic regulation of brain development, plasticity, and response to early-life stressSemantic proximity Read

Annual Research Review: Developmental considerations of gene by environment interactions.Semantic proximity Read

Experience-based brain development: Scientific underpinnings of the importance of early child development in a global worldSemantic proximity Read

Depression from childhood into late adolescence: Influence of gender, development, genetic susceptibility, and peer stress.Semantic proximity Read

Annual Research Review: Epigenetic mechanisms and environmental shaping of the brain during sensitive periods of developmentSemantic proximity Read

Social Origins of Developmental Risk for Mental and Physical IllnessSemantic proximity Read