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Structural characterization of LsrK to target quorum sensing and comparison between X-ray and homology model

2020-09-03

Abstract excerpt

<h4>ABSTRACT</h4> Quorum sensing is being investigated as an alternative therapeutic strategy in antibacterial drug discovery to combat bacterial resistance. LsrK is an autoinducer-2 kinase, playing a key role in the phosphorylation of autoinducer-2 (AI-2) signalling molecules involved in quorum sensing. Inhibiting LsrK could result in reduced pathogenicity by interfering with the quorum sensing signalling. Previ...

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Literature Corpus work
dd018a9f-c391-5db0-bdad-93b4bb86d1c0
DOI
10.1101/2020.09.03.281394
Open publication

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Structural characterization of LsrK to target quorum sensing and comparison between X-ray and homology modelDOI 10.1101/2020.09.03.281394
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