Article

Screening strategies for prostate cancer in Israeli BRCA pathogenic sequence variant carriers

2024-11-26

Abstract excerpt

<title>Abstract</title> <p>Men carrying germline pathogenic sequence variants (PSVs) in the <italic>BRCA1/2</italic> (BRCA- PSV) are at an increased risk for early onset aggressive prostate cancer (PrCa). Screening strategies, including prostate MRI (pMRI), are advocated, yet their clinical utility remains uncertain. To this end we employed Decision Curve Analysis (DCA) to compare screening based on either family...

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Literature Corpus work: dcc07328-976e-519b-b5bf-611dc71b7029
DOI: 10.21203/rs.3.rs-5341489/v1

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