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Article

Ductal Carcinoma In Situ (DCIS) Diagnosed by MRI-Guided Biopsy among BRCA1/BRCA2 Mutation Carriers.

The breast journal - 1 Jan 2022

Faermann Renata, Friedman Eitan, Kaidar-Person Orit, Weidenfeld Jonathan, Brodsky Malka, Shalmon Anat, Halshtok Neiman Osnat, Gotlieb Michael, Yagil Yael, Samoocha David, Madorsky Feldman Dana, Sklair-Levy Miri

Abstract excerpt

Background: While BRCA1/BRCA2 pathogenic sequence variants (PSVs) clearly confer an increased risk for invasive breast cancer, the extent to which these mutant alleles increase DCIS risk is less clear. Objective: To assess the rate of detection over a 5-year period, and MRI imaging features of pure noncalcified DCIS in a cohort of Israeli BRCA1/BRCA2 PSV carriers attending a high-risk clinic from 2015 to 2020....

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Identifiers

PMID: 36349178
DOI: 10.1155/2022/4317693
PMCID: PMC9633198

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