Article

The serotonin reuptake inhibitor Fluoxetine inhibits SARS-CoV-2

2020-06-14

Abstract excerpt

To circumvent time-consuming clinical trials, testing whether existing drugs are effective inhibitors of SARS-CoV-2, has led to the discovery of Remdesivir. We decided to follow this path and screened approved medications “off-label” against SARS-CoV-2. In these screenings, Fluoxetine inhibited SARS-CoV-2 at a concentration of 0.8µg/ml significantly, and the EC50 was determined with 387ng/ml. Fluoxetine is a racem...

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Literature Corpus work: dcc06369-6003-5bac-ba35-f782cceebc3e
DOI: 10.1101/2020.06.14.150490

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