Article

LigEGFR: Spatial graph embedding and molecular descriptors assisted bioactivity prediction of ligand molecules for epidermal growth factor receptor on a cell line-based dataset

2020-12-24

Abstract excerpt

<h4> A bstract </h4> <h4>Motivation</h4> Lung cancer is a chronic non-communicable disease and is the cancer with the world’s highest incidence in the 21 st century. One of the leading mechanisms underlying the development of lung cancer in nonsmokers is an amplification of the epidermal growth factor receptor (EGFR) gene. However, laboratories employing conventional processes of drug discovery and developmen...

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Literature Corpus work: dc3a42b7-d26a-5ae4-be44-b89109d41968
DOI: 10.1101/2020.12.24.423424

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