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Optimizing single-cell RNA sequencing methods for human colon biopsies: droplet-based vs. picowell-based platforms

2024-06-28

Abstract excerpt

<h4>Background & Aims</h4> Single-cell RNA sequencing (scRNA) has empowered many insights into gastrointestinal microenvironments. However, profiling human biopsies using droplet-based scRNA (D-scRNA) is challenging since it requires immediate processing to minimize epithelial cell damage. In contrast, picowell-based (P-scRNA) platforms permit short-term frozen storage before sequencing. We compared P- and D-scRN...

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Literature Corpus work: dc14f169-4f73-5517-8c14-704d32be67a5
DOI: 10.1101/2024.06.24.600526

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