Article

GADD34 activates p53 and may have utility as a marker of atherosclerosis

2022-09-23

Abstract excerpt

We previously identified growth arrest and DNA-damage-inducible gene 34 (GADD34) as a marker of ischemic stroke. In the present study, serum levels of anti-GADD34 antibodies were found to be significantly higher in patients with acute ischemic stroke or chronic kidney disease compared to healthy donors. We then examined the biological function of GADD34 by transfection into human osteosarcoma U2OS cells. Knockdown...

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Literature Corpus work: dbcf030e-6f48-588e-9d9c-4648b7e21088
DOI: 10.21203/rs.3.rs-2088682/v1

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