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Article

Activation of Gadd34 by diverse apoptotic signals and suppression of its growth inhibitory effects by apoptotic inhibitors.

International journal of cancer - 20 Feb 2001

Hollander M C, Sheikh M S, Yu K, Zhan Q, Iglesias M, Woodworth C, Fornace A J

Abstract excerpt

DNA damage has many cellular consequences including, in some cases, apoptosis. Expression of Gadd34 was shown to be increased by ionizing radiation only in cells that undergo rapid apoptosis following this treatment. The effects of various other apoptosis-inducing agents as well as apoptosis-inhibiting genes on regulation of Gadd34 were investigated. In many cell types, agents which have been reported to lead to...

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PMID: 11241327
DOI: 10.1002/1097-0215(20010220)96:1<22::aid-ijc3>3.0.co;2-k

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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