Back to search

Article

Functional Gene Signature Offers a Powerful Tool for Characterizing Clinicopathological Features and Depicting Tumor Immune Microenvironment of Colorectal Cancer

2024-04-30

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Colorectal cancer, a prevalent malignancy worldwide, poses a significant challenge due to the lack of effective prognostic tools. In this study, we aimed to develop a functional gene signature to stratify colorectal cancer patients into different groups with distinct characteristics, which will greatly facilitate disease prediction. <h4>Results:</h4> Patients co...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
db88e13f-4684-5b1e-b79e-01c47624bace
DOI
10.21203/rs.3.rs-4297513/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Functional Gene Signature Offers a Powerful Tool for Characterizing Clinicopathological Features and Depicting Tumor Immune Microenvironment of Colorectal CancerDOI 10.21203/rs.3.rs-4297513/v1
A Comprehensive Multi-Omics Analysis Identifies a Robust Scoring System for Cancer-Associated Fibroblasts and Intervention Targets in Colorectal CancerSemantic proximity
Integrative analysis of the immunological features and immunotherapy response of positive regulators of T cell function in colorectal cancerSemantic proximity
Integrated single-cell and bulk RNA-seq for constructing a prognostic risk model of immune-related genes in colorectal cancerSemantic proximity
Development of molecular subtype specific prognostic marker signature in immune response associated colon cancer through fuzzy based transcriptomic approachSemantic proximity
CAF signature predicts the prognosis of colorectal cancer patients: A retrospective study based on bulk RNA sequencing and single-cell RNA sequencing dataSemantic proximity
Establishment and Validation of a Genetic Label Associated With M2 Macrophage Infiltration to Predict Survival in Colon Cancer Patients and Assist ImmunotherapySemantic proximity
Epithelial-Mesenchymal Transformation Related Genomic Analysis Reveals Prognostic And Immunogenic Significance In Colorectal CancerSemantic proximity
Identification of Tumor Microenvironment-related Prognostic Genes in Colorectal Cancer based on Bioinformatic MethodsSemantic proximity
Comprehensive evaluation of immunological attributes and immunotherapy responses of positive T cell function regulators in colorectal cancer.Semantic proximity
Integrated single-cell and bulk RNA-seq analysis reveals a novel T-cell signature for prognosis and treatment response in colorectal cancerSemantic proximity
Development of an immune-related gene prognostic risk model and identification of an Immune infiltration signature in the tumor microenvironment of colon cancerSemantic proximity
Multi-omics Analysis and Functional Characterization of the TIMP1 in Colorectal CancerSemantic proximity
Select a neighboring publication to make it the new centre.