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Article

Altered metabolic profiles of dermatomyositis with different myositis-specific autoantibodies associated with clinical phenotype.

Frontiers in immunology - 1 Jan 2024

Wang Nan, Shang Lili, Liang Zhaojun, Feng Min, Wang Yanlin, Gao Chong, Luo Jing

Abstract excerpt

Introduction: Dermatomyositis (DM) is an idiopathic inflammatory myopathy. Because of clinical heterogeneity, the metabolite profile of DM patients with different myositis-specific autoantibodies (MSAs) remains elusive. This study aimed to explore the metabolomics characteristics of the serum in DM with different MSAs, low or high disease activity, and interstitial lung disease. Methods: Untargeted metabolomics...

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Identifiers

PMID: 39654882
DOI: 10.3389/fimmu.2024.1429010
PMCID: PMC11625817

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