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Tear Proteomics Reveals RAGE and NLRP3 Inflammasome Pathway Activation in Lacrimal Glands of a Sjögren’s Disease Mouse Model

2026-07-20

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose</h4> To characterize tear proteome changes in male non-obese diabetic (NOD) mice with Sjögren’s disease (SjD)-like autoimmune dacryoadenitis and determine whether identified tear proteins are associated with lacrimal gland (LG) pathogenesis. <h4>Methods</h4> Tears were collected from 14-week-old male NOD mice and age-matched male BALB/c controls and analyzed by tandem mass tag (TMT...

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Literature Corpus work
db78ef10-292c-5b6a-b0c1-a4da07a8d401
DOI
10.64898/2026.07.15.738677
Open publication

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Tear Proteomics Reveals RAGE and NLRP3 Inflammasome Pathway Activation in Lacrimal Glands of a Sjögren’s Disease Mouse ModelDOI 10.64898/2026.07.15.738677
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