Article

Placental transcriptome profiling in congenital Chagas disease: gene networks associated with transmission

2025-09-21

Abstract excerpt

Chagas disease, caused by Trypanosoma cruzi , affects over seven million people globally. Vertical transmission during pregnancy significantly contributes to the urban spread of the disease, even in non-endemic areas. The placental barrier plays a key role in preventing fetal infection, although the molecular mechanisms underlying congenital transmission remain unclear. To identify placental factors associated wi...

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Literature Corpus work: db65e1ce-e2f1-52fe-b9b8-d9413206e08d
DOI: 10.1101/2025.09.17.676751

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