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Article

Different genotypes of Trypanosoma cruzi produce distinctive placental environment genetic response in chronic experimental infection.

PLoS neglected tropical diseases - 1 Mar 2017

Juiz Natalia Anahí, Solana María Elisa, Acevedo Gonzalo Raúl, Benatar Alejandro Francisco, Ramirez Juan Carlos, da Costa Priscilla Almeida, Macedo Andrea Mara, Longhi Silvia Andrea, Schijman Alejandro G

Abstract excerpt

Congenital infection of Trypanosoma cruzi allows transmission of this parasite through generations. Despite the problematic that this entails, little is known about the placenta environment genetic response produced against infection. We performed functional genomics by microarray analysis in C57Bl/6J mice comparing placentas from uninfected animals and from animals infected with two different T. cruzi strains:...

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Identifiers

PMID: 28273076
DOI: 10.1371/journal.pntd.0005436
PMCID: PMC5358786

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