Article
Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease.
Cell host & microbe - 19 May 2011
Bloom Seth M, Bijanki Vinieth N, Nava Gerardo M, Sun Lulu, Malvin Nicole P, Donermeyer David L, Dunne W Michael, Allen Paul M, Stappenbeck Thaddeus S
Abstract excerpt
The intestinal microbiota is important for induction of inflammatory bowel disease (IBD). IBD is associated with complex shifts in microbiota composition, but it is unclear whether specific bacterial subsets induce IBD and, if so, whether their proportions in the microbiota are altered during disease. Here, we fulfilled Koch's postulates in host-genotype-specific fashion using a mouse model of IBD with...
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