Article
Pathobionts of the gastrointestinal microbiota and inflammatory disease.
Current opinion in immunology - 1 Aug 2011
Chow Janet, Tang Haiqing, Mazmanian Sarkis K
Abstract excerpt
Our immune system is charged with the vital mission of identifying invading pathogens and mounting proper inflammatory responses. During the process of clearing infections, the immune system often causes considerable tissue damage. Conversely, if the target of immunity is a member of the resident microbiota, uncontrolled inflammation may lead to host pathology in the absence of infectious agents. Recent evidence...
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