Article
Cross-tissue organization of the fibroblast lineage.
Nature - 1 May 2021
Buechler Matthew B, Pradhan Rachana N, Krishnamurty Akshay T, Cox Christian, Calviello Aslihan Karabacak, Wang Amber W, Yang Yeqing Angela, Tam Lucinda, Caothien Roger, Roose-Girma Merone, Modrusan Zora, Arron Joseph R, Bourgon Richard, Müller Sören, Turley Shannon J
Abstract excerpt
Fibroblasts are non-haematopoietic structural cells that define the architecture of organs, support the homeostasis of tissue-resident cells and have key roles in fibrosis, cancer, autoimmunity and wound healing1. Recent studies have described fibroblast heterogeneity within individual tissues1. However, the field lacks a characterization of fibroblasts at single-cell resolution across tissues in healthy and...
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