Article

Decoding human placental cellular and molecular responses to obesity and fetal growth

2025-01-28

Abstract excerpt

Maternal obesity increases risk of large-for-gestational-age (LGA) births and subsequent cardiometabolic disorders in offspring. To identify placental signatures associated with these outcomes, we performed single-nucleus RNAseq on placentas from women with obesity delivering appropriate-for-gestational-age (AGA) or LGA infants, compared to normal-weight controls. In maternal obesity, regardless of fetal growth, s...

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Literature Corpus work: daa54064-8f60-5bca-b08a-a889b4f4922c
DOI: 10.1101/2025.01.27.634981

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