Article
Fibroproliferation in chronic lung allograft dysfunction: Association of mesenchymal cells in bronchoalveolar lavage with phenotypes and survival.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Aug 2020
Combs Michael P, Xia Meng, Wheeler David S, Belloli Elizabeth A, Walker Natalie M, Braeuer Russell R, Lyu Dennis M, Murray Susan, Lama Vibha N
Abstract excerpt
BACKGROUND: Chronic lung allograft dysfunction (CLAD), the primary cause of poor outcome after lung transplantation, arises from fibrotic remodeling of the allograft and presents as diverse clinical phenotypes with variable courses. Here, we investigate whether bronchoalveolar lavage (BAL) mesenchymal cell activity at CLAD onset can inform regarding disease phenotype, progression, and survival. METHODS:...
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