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The Functional Order (FunOrder) tool – Identification of essential biosynthetic genes through computational molecular co-evolution

2021-02-01

Abstract excerpt

<h4>ABSTRACT</h4> Secondary metabolites (SMs) are a vast group of compounds with different structures and properties. Humankind uses SMs as drugs, food additives, dyes, and as monomers for novel plastics. In many cases, the biosynthesis of SMs is catalysed by enzymes whose corresponding genes are co-localized in the genome in biosynthetic gene clusters (BGCs). Notably, BGCs may contain so-called gap genes, that a...

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Literature Corpus work: da6e5725-eb08-51c5-a474-d86d7ad718b3
DOI: 10.1101/2021.01.29.428829

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