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An interpreted atlas of biosynthetic gene clusters from 1,000 fungal genomes

3 May 2021

Abstract excerpt

Fungi are prolific producers of natural products, compounds which have had a large societal impact as pharmaceuticals, mycotoxins, and agrochemicals. Despite the availability of over 1,000 fungal genomes and several decades of compound discovery efforts from fungi, the biosynthetic gene clusters (BGCs) encoded by these genomes and the associated chemical space have yet to be analyzed systematically. Here, we...

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PMID: 33941694
DOI: 10.1073/pnas.2020230118

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