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Global Analysis of Natural Products Biosynthetic Diversity Encoded in Fungal Genomes

13 Sept 2024

Abstract excerpt

Fungal secondary metabolites (SMs) represent an invaluable source of therapeutic drugs. Genomics-based approaches to SM discovery have revealed a vast and largely untapped biosynthetic potential within fungal genomes. Here, we used the publicly available fungal genome sequences from the NCBI public database, as well as tools such as antiSMASH, BIG-SLiCE, etc., to analyze a total of 11,598 fungal genomes,...

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PMID: 39330413
DOI: 10.3390/jof10090653

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