Article

Social but not metabolic stress in adolescence alters offspring social behavior and oocyte Crhr1/miR-34c expression: a four-generation study

2025-02-04

Abstract excerpt

<title>Abstract</title> <p>Social stress has long-term behavioral and physiological consequences, and studies in male rodents show that it alters sperm miRNA expression and behavior in offspring. The direct and transgenerational impact of social stress in females on brain and germline has not been studied, and its effect on offspring phenotypes remains unknown. In this study, we compared the impact of social and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: da6b6409-8b80-5d73-96d8-cfaf4838a5c7
DOI: 10.21203/rs.3.rs-5796995/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Social but not metabolic stress in adolescence alters offspring social behavior and oocyte Crhr1/miR-34c expression: a four-generation studyDOI 10.21203/rs.3.rs-5796995/v1Read

Pre-reproductive stress in adolescent female rats alters oocyte microRNA expression and offspring phenotypes: pharmacological interventions and putative mechanisms.Semantic proximity Read

Subregion-Specific Transcriptomic Profiling of Rat Brain Reveals Sex-Distinct Gene Expression Impacted by Adolescent StressSemantic proximity Read

Social isolation stress in adolescence, but not adulthood, produces hypersocial behavior in adult male and female C57BL/6J miceSemantic proximity Read

Early life stress induces social behavioral deficits and peripheral biomarker alterations in adolescence that perpetuate intergenerationallySemantic proximity Read

Chronic prenatal corticosterone exposure alters postpartum maternal behavior and shapes sex-specific offspring outcomesSemantic proximity Read

Epigenetic Influence of Stress and the Social EnvironmentSemantic proximity Read

Environmental Intervention as a Therapy for Adverse Programming by Ancestral StressSemantic proximity Read

Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring.Semantic proximity Read

Peripubertal antagonism of corticotropin-releasing factor receptor 1 results in sustained changes in behavioral plasticity and the transcriptomic profile of the amygdalaSemantic proximity Read

Prenatal stress produces sex-specific changes in depression-like behavior in rats: implications for increased vulnerability in femalesSemantic proximity Read

A next-generation sequencing study on mechanisms by which restraint and social instability stresses of male mice alter offspring anxiety-like behavior.Semantic proximity Read

Parental life events cause behavioral difference among offspring: Adult pre-gestational restraint stress reduces anxiety across generations.Semantic proximity Read