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Article

Environmental Intervention as a Therapy for Adverse Programming by Ancestral Stress

24 Nov 2016

Abstract excerpt

Ancestral stress can program stress sensitivity and health trajectories across multiple generations. While ancestral stress is uncontrollable to the filial generations, it is critical to identify therapies that overcome transgenerational programming. Here we report that prenatal stress in rats generates a transgenerationally heritable endocrine and epigenetic footprint and elevated stress sensitivity which can be...

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PMID: 27883060
DOI: 10.1038/srep37814

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