Article

Statistical Methods for Microrheology of Airway Mucus with Extreme Heterogeneity

2023-11-21

Abstract excerpt

The mucus lining of the human airway epithelium contains two gel-forming mucins, MUC5B and MUC5AC. During progression of cystic fibrosis (CF), mucus hyper-concentrates as its mucin ratio changes, coinciding with formation of insoluble, dense mucus flakes. We explore rheological heterogeneity of this pathology with reconstituted mucus matching three stages of CF progression and particle-tracking of 200 nm and 1 mic...

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Literature Corpus work: da46da2f-0275-5a6b-86c8-a5f98da24b23
DOI: 10.1101/2023.11.20.567244

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