Article
Food restriction engages prefrontal corticostriatal cells and local microcircuitry to drive the decision to run vs conserve energy
2020-10-16
Abstract excerpt
<h4>ABSTRACT</h4> Food restriction (FR) evokes running, which may promote adaptive foraging in times of food scarcity, but can become lethal if energy expenditure exceeds caloric availability. Here, we demonstrate that chemogenetic activation of either the general medial prefrontal cortex (mPFC) pyramidal cell population, or the subpopulation projecting to dorsal striatum (DS) drives running specifically during h...
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Identifiers and source
- Literature Corpus work
- da29a0ad-0ef8-5fb8-afb7-4b5b19eae099
- DOI
- 10.1101/2020.10.16.342808
