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Food restriction engages prefrontal corticostriatal cells and local microcircuitry to drive the decision to run vs conserve energy

2020-10-16

Abstract excerpt

<h4>ABSTRACT</h4> Food restriction (FR) evokes running, which may promote adaptive foraging in times of food scarcity, but can become lethal if energy expenditure exceeds caloric availability. Here, we demonstrate that chemogenetic activation of either the general medial prefrontal cortex (mPFC) pyramidal cell population, or the subpopulation projecting to dorsal striatum (DS) drives running specifically during h...

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Literature Corpus work
da29a0ad-0ef8-5fb8-afb7-4b5b19eae099
DOI
10.1101/2020.10.16.342808
Open publication

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Food restriction engages prefrontal corticostriatal cells and local microcircuitry to drive the decision to run vs conserve energyDOI 10.1101/2020.10.16.342808
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