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Article

Relationships between phenotypic differences in punishment behaviour and prefrontal cortex network engagement.

Neurobiology of learning and memory - 1 May 2026

Lou Min, Shen Michelle H, Al-Saddik Saraa, Keevers Luke J, Jean-Richard-Dit-Bressel Philip

Abstract excerpt

Avoiding actions with negative consequences is fundamental to adaptive behaviour, yet individuals differ drastically in their tendencies to avoid to punishment. Using a conditioned punishment task in male and female rats, we replicate findings of a bimodal distribution of punishment avoidance, and identify four distinct behavioural phenotypes (Sensitive, Hypersensitive, Insensitive, Generalised) that differed in...

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Identifiers

PMID: 42128291
DOI: 10.1016/j.nlm.2026.108167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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