Article
Genetic subtype differences in neural circuitry of food motivation in Prader-Willi syndrome.
International journal of obesity (2005) - 1 Feb 2009
Holsen L M, Zarcone J R, Chambers R, Butler M G, Bittel D C, Brooks W M, Thompson T I, Savage C R
Abstract excerpt
BACKGROUND: Differences in behavioral phenotypes between the two most common subtypes of Prader-Willi syndrome (PWS) (chromosome 15q deletions and maternal uniparental disomy 15 (UPD) indicate that distinct neural networks may be affected. Though both subtypes display hyperphagia, the deletion su...
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