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A multiplex droplet digital PCR assay for non-invasive prenatal testing of fetal aneuploidies

1 Jan 2019

Abstract excerpt

Higher multiplexing in droplet digital PCR (ddPCR) can simplify the detection process of ddPCR-based non-invasive prenatal testing (NIPT) and improve its reliability, making it a practical approach in clinical practice. However, a high level of multiplex ddPCR-based NIPT has rarely been reported. In this study, we developed a multiplex ddPCR assay using universal locked nucleic acid (LNA) probes to reliably...

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PMID: 30663740
DOI: 10.1039/c8an02018c

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