Article

Computational Prediction of the Molecular Mechanism of Statin Group of Drugs Against SARS-CoV-2 Pathogenesis

2021-08-16

Abstract excerpt

<h4>Background: </h4> The COVID-19 pandemic had raised a severe health concern across the globe, as most countries are fighting with the second wave of SARS-CoV-2 infection. Although several vaccines had cleared the clinical trials and are being administered in different countries, the degree of protection varies due to the emergence of novel viral strains. Moreover, no antiviral drug against SARS-CoV-2 was report...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d9e2056f-7431-5525-b50d-34e72a61e757
DOI: 10.21203/rs.3.rs-783266/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Computational Prediction of the Molecular Mechanism of Statin Group of Drugs Against SARS-CoV-2 PathogenesisDOI 10.21203/rs.3.rs-783266/v1Read

Atorvastatin effectively inhibits late replicative cycle steps of SARS-CoV-2 <i>in vitro</i>Semantic proximity Read

A new proposed mechanism of some known drugs targeting the SARS-CoV-2 spike glycoprotein using molecular dockingSemantic proximity Read

Molecular Basis of SARS-CoV‑2 Infection and Rational Design of Potential Antiviral Agents: Modeling and Simulation ApproachesSemantic proximity Read

The Impact of D614G Mutation of SARS-COV-2 on the Efficacy of Anti-viral Drugs: A Comparative Molecular Docking and Molecular Dynamics Study.Semantic proximity Read

In-silico analysis of potential interaction of drugs and the SARS-CoV-2 spike proteinSemantic proximity Read

Molecular Docking Reveals Ivermectin and Remdesivir as Potential Repurposed Drugs Against SARS-CoV-2Semantic proximity Read

Genomics functional analysis and drug screening of SARS-CoV-2Semantic proximity Read

In silico screening of known small molecules to bind ACE2 specific RBD on Spike glycoprotein of SARS-CoV-2 for repurposing against COVID-19Semantic proximity Read

Inhibition potential of natural flavonoids against selected omicron (B.1.19) mutations in the spike receptor binding domain of SARS-CoV-2: a molecular modeling approach.Semantic proximity Read

A recombinant fragment of Human surfactant protein D binds Spike protein and inhibits infectivity and replication of SARS-CoV-2 in clinical samplesSemantic proximity Read

Elucidation of the interactions between SARS-CoV-2 Spike protein and wild and mutant types of IFITM proteins by <i>in silico</i> methodsSemantic proximity Read

Bioinformatics approaches to understand the interactions between the SARS corona Virus (SARS-CoV19) with stranded drugs of anti-retro viral treatment, Influenza and Malaria.Semantic proximity Read