Article

A new proposed mechanism of some known drugs targeting the SARS-CoV-2 spike glycoprotein using molecular docking

2020-11-13

Abstract excerpt

COVID-19 is caused by the novel enveloped beta-coronavirus with a genomic RNA closely related to severe acute respiratory syndrome-corona virus (SARS-CoV) and is named coronavirus 2 (SARS-CoV-2). The receptor binding domain (RBD) of the S-protein interacts with the human ACE-2 receptor that enables the initiation of viral entry. Hence, blocking the S-protein interactions by means of synthetic compounds mark the pi...

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Literature Corpus work: fa3c7cc9-c2e5-596b-838e-8ac1f3bb081e
DOI: 10.21203/rs.3.rs-105677/v1

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