Article

A recombinant fragment of Human surfactant protein D binds Spike protein and inhibits infectivity and replication of SARS-CoV-2 in clinical samples

2020-12-18

Abstract excerpt

<h4>Rationale</h4> COVID-19 is an acute infectious disease caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Human surfactant protein D (SP-D) is known to interact with spike protein of SARS-CoV, but its immune-surveillance against SARS-CoV-2 is not known. <h4>Objective</h4> This study aimed to examine the potential of a recombinant fragment of human SP-D (rfhSP-D) as an inhibitor of re...

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Literature Corpus work: e3044434-cf3e-559c-b004-4370e2788e32
DOI: 10.1101/2020.12.18.423415

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