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rAAV prostaglandin-based gene therapy lowers intraocular pressure and preserves optic nerve health in glaucomatous DBA/2J mice

2026-03-31

Abstract excerpt

<h4>ABSTRACT</h4> Open-angle glaucoma (OAG) affects approximately 57.5 million individuals worldwide and is characterized by the progressive loss of retinal ganglion cells (RGC) and irreversible optic nerve damage resulting from chronic ocular hypertension. Intraocular pressure (IOP) is the only major modifiable risk factor in OAG and clinical treatments necessarily aim to lower IOP in order to preserve RGCs and...

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Literature Corpus work
d9c0e722-3cee-59e3-b7ec-62bf63eda109
DOI
10.64898/2026.03.27.714838
Open publication

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rAAV prostaglandin-based gene therapy lowers intraocular pressure and preserves optic nerve health in glaucomatous DBA/2J miceDOI 10.64898/2026.03.27.714838
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