Article

Fingolimod Regulates BDNF-AS and HOTAIR Expression in Multiple Sclerosis Patients

2021-08-10

Abstract excerpt

Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, is expressed by neurons and glial cells in the central nervous system (CNS). In the CNS, BDNF is responsible for neuroprotection and neurogenesis. Recent studies showed that the Fingolimod, the first oral medicine for relapsing-remitting multiple sclerosis (RR-MS), induces BDNF expression. Besides, It is well demonstrated that long nonc...

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Literature Corpus work: d99ec381-5a58-51b7-9c2e-faedde347caf
DOI: 10.1101/2021.08.09.455760

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