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Effects of CwlM, a peptidoglycan synthesis regulator, on beta-lactam resistance and host-pathogen interactions

2025-07-08

Abstract excerpt

<h4>Background</h4> The emergence and spread of multidrug-resistant (MDR) strains of Mycobacterium tuberculosis ( Mtb ) urge the development of novel drugs and efficient therapeutic programs. A recent study aiming to uncover differential beta-lactam susceptibility phenotypes in clinical strains of Mtb found that the M237V substitution in cwlM ( Rv3915 ) was associated with increased susceptibility to amoxici...

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Literature Corpus work
d983ad11-b7e1-50c8-a2d0-c4bdccefd2a3
DOI
10.1101/2025.07.08.663695
Open publication

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