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Disease classification for whole blood DNA methylation: meta-analysis, missing values imputation, and XAI

2022-05-11

Abstract excerpt

<h4>Background</h4> DNA methylation has a significant effect on gene expression and can be associated with various diseases. Meta-analysis of available DNA methylation datasets requires development of a specific pipeline for joint data processing. <h4>Results</h4> We propose a comprehensive approach of combined DNA methylation datasets to classify controls and patients. The solution includes data harmonization,...

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Literature Corpus work
d94a2891-6875-5150-ba2d-e98c08f50e07
DOI
10.1101/2022.05.10.491404
Open publication

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