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Monoclonal antibodies targeting surface exposed epitopes of <i>Candida albicans</i> cell wall proteins confer <i>in vivo</i> protection in an infection model

2021-09-29

Abstract excerpt

MAb based immunotherapies targeting systemic and deep-seated fungal infections are still in their early stages of development with currently no licensed antifungal mAbs available for patients at risk. The cell wall glycoproteins of Candida albicans are of particular interest as potential targets for therapeutic antibody generation due to their extracellular location and key involvement in fungal pathogenesis. Her...

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Literature Corpus work
d93dc964-85a2-547d-b0a1-a34fedf053d5
DOI
10.1101/2021.09.29.462385
Open publication

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Monoclonal antibodies targeting surface exposed epitopes of <i>Candida albicans</i> cell wall proteins confer <i>in vivo</i> protection in an infection modelDOI 10.1101/2021.09.29.462385
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