Article

A High-Performance Liquid Chromatography-Mass Spectrometry method for simultaneous determination of dolutegravir, nevirapine, efavirenz, rifampicin and rifapentine concentrations in human plasma

2025-06-09

Abstract excerpt

<h4>ABSTRACT</h4> Variations in clinical pharmacokinetics and genetics, and polypharmacy affect attainment of target drug concentrations in HIV-TB co-infected patients. However, scarcity of analytical methods hinders drug concentration measurement for therapeutic drug monitoring in this doubly vulnerable population in low-and-middle income countries. This study aimed to develop and validate an LC-MS method for sim...

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Literature Corpus work: d93596ca-34b6-59d0-b829-913391167d0f
DOI: 10.1101/2025.06.08.25329229

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A High-Performance Liquid Chromatography-Mass Spectrometry method for simultaneous determination of dolutegravir, nevirapine, efavirenz, rifampicin and rifapentine concentrations in human plasmaDOI 10.1101/2025.06.08.25329229Read

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