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Article

Development and Validation of Voriconazole Concentration by LC-MS-MS: Applied in Clinical Implementation.

Journal of clinical laboratory analysis - 1 Jan 2017

Prommas Santirat, Puangpetch Apichaya, Jenjirattithigarn Nuttawut, Chuwongwattana Sumonrat, Jantararoungtong Thawinee, Koomdee Napatrupron, Santon Siwalee, Chamnanphon Montri, Sukasem Chonlaphat

Abstract excerpt

BACKGROUND: Voriconazole (VRZ) is a triazole antifungal used for treatment of invasive fungal infection, which is a life-threatening condition. Therapeutic drug monitoring is recommended for identifying the optimal dose in patients who have hepatic/renal impairment or reduced function of the CYP2C19 metabolizing enzyme. METHODS: One hundred microliters of sample plasma was extracted by protein precipitated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27337994
DOI: 10.1002/jcla.22011
PMCID: PMC6816790

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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