Article

Ciliary sensing in tanycytes couples nutrient availability to metabolic regulation

2025-12-31

Abstract excerpt

Body homeostasis relies on accurate communication between the brain and the periphery. Disruption of this communication can contribute to disease. Tanycytes are located at the interface of the cerebrospinal fluid (CSF), bloodstream, and hypothalamus, where they sense circulating nutrients and regulate neuroendocrine axes and metabolism. However, the mechanisms by which they sense CSF signals remain largely unclear...

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Literature Corpus work: d8f04cbc-2005-5ddd-8462-361161705cde
DOI: 10.64898/2025.12.31.697168

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