Article

Common and Rare Variant Contributions to Bradyarrhythmias from Multi-Ancestry Meta-Analyses

2023-09-25

Abstract excerpt

<h4>ABSTRACT</h4> To broaden our understanding of bradyarrhythmias and diseases of the cardiac conduction system, we performed cross-sectional multi-ancestry genome-wide association study meta-analyses in up to 1.3 million individuals for sinus node dysfunction (SND), distal conduction disease (DCD), and pacemaker implantation (PM). We evaluated the biological relevance of bradyarrhythmia loci by analyses of trans...

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Literature Corpus work: d8b0e5e6-2226-5dd8-89d0-3d5e339732c2
DOI: 10.1101/2023.09.24.23295485

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